Quercetin is a powerful antioxidant and anti-inflammatory compound found in apples, onions, and berries. It helps neutralize free radicals that cause oxidative stress, which can lead to chronic inflammation and cellular damage over time.

This flavonoid is especially beneficial for dogs with allergies, sensitivities, or immune-related issues. Quercetin supports the immune system’s natural defenses and may help regulate histamine responses that cause itching, redness, or hot spots. It also promotes healthy circulation and may contribute to maintaining stable blood pressure.

In active dogs, Quercetin can support faster recovery by reducing muscle soreness and supporting joint flexibility. Whether your dog is aging, highly active, or just prone to seasonal allergies, Quercetin delivers daily protection that keeps them feeling balanced and resilient.

Rutin is a powerful antioxidant flavonoid found in apples, citrus fruits, and buckwheat. It’s known for its ability to strengthen blood vessels and support healthy circulation, making it especially valuable for dogs with cardiovascular concerns or aging joints. By helping maintain flexible, resilient capillaries, Rutin may reduce swelling and discomfort in dogs with poor mobility or inflammatory issues.

This compound also supports a healthy inflammatory response, helping to manage stiffness and discomfort in dogs that are active, recovering, or simply aging. Rutin works well in combination with other flavonoids, making it a foundational compound in holistic wellness formulas.

In addition to cardiovascular support, Rutin has been studied for its ability to help stabilize histamines, similar to Quercetin. This may offer a second layer of allergy defense in sensitive pups.

Fisetin is a neuroprotective flavonoid most commonly found in strawberries, apples, and onions. It plays a key role in protecting brain cells, reducing oxidative stress, and supporting memory and learning. Fisetin has been studied for its potential to delay age-related cognitive decline, making it especially beneficial for senior dogs or those showing early signs of cognitive dysfunction.

Its antioxidant power also contributes to overall cellular health, helping to defend the body’s tissues—including the nervous system—from oxidative damage. Fisetin may also assist in regulating blood sugar levels and improving insulin sensitivity, making it a smart choice for dogs with metabolic or energy balance concerns.

Dogs of any age can benefit from Fisetin, but it's particularly helpful for aging companions who need support staying sharp, focused, and mentally engaged. It pairs well with other flavonoids for full-spectrum brain and body wellness.

Baicalin is a flavonoid extracted from the root of the Scutellaria baicalensis plant, also known as Chinese skullcap. It’s best known for its strong anti-inflammatory and antioxidant effects, making it a powerful ally for dogs dealing with chronic discomfort, immune imbalances, or age-related conditions.

Baicalin helps protect cells from oxidative stress and has been shown to modulate the immune system, reducing excessive inflammatory responses without suppressing essential immune activity. This makes it especially useful for dogs with joint issues, skin irritation, or inflammation-driven sensitivities.

Beyond inflammation control, Baicalin also offers neuroprotective benefits and has shown promise in studies focused on longevity and brain aging. Its broad-spectrum activity makes it a standout ingredient in flavonoid-based wellness formulas for dogs needing long-term support.

Chrysin is a natural flavonoid found in passionflower and honeycomb, known for its calming properties and role in supporting hormonal balance. It’s often used to help ease stress and anxiety, making it ideal for dogs that struggle with nervousness, reactivity, or separation-related issues.

One of Chrysin’s unique features is its ability to inhibit the enzyme aromatase, which converts testosterone into estrogen. This may help maintain healthy hormone levels, particularly in male dogs, and support muscle tone, recovery, and balanced energy. For highly active dogs or those with performance-related stress, Chrysin offers both mental and metabolic support.

Chrysin also contributes antioxidant and anti-inflammatory benefits, helping to protect the body and brain from stress-related damage. Whether your dog is anxious during storms or just needs help staying balanced, Chrysin offers a natural, non-sedating way to promote calm and focus.

Kaempferol is a powerful antioxidant flavonoid found in leafy greens like kale, spinach, and broccoli. It plays a key role in reducing inflammation, protecting cells from oxidative damage, and supporting heart health. For dogs, it offers broad wellness benefits that support long-term vitality and resilience.

Kaempferol has been studied for its ability to improve blood vessel function, reduce blood pressure, and help regulate inflammatory pathways throughout the body. This makes it especially useful for dogs with joint discomfort, cardiovascular concerns, or chronic inflammatory conditions. It also contributes to cellular repair and may assist in protecting against certain age-related diseases.

As part of a daily flavonoid blend, Kaempferol delivers foundational support that benefits dogs at every life stage—from energetic pups to aging companions who need help staying strong and mobile.

Luteolin is a versatile flavonoid found in parsley, celery, and thyme. Known for its strong antioxidant and anti-inflammatory effects, Luteolin plays a vital role in protecting the brain, calming allergic reactions, and supporting immune balance. It has been studied for its neuroprotective properties and is especially valuable for dogs needing cognitive or immune system support.

Luteolin helps reduce oxidative stress in brain cells and may improve memory and learning, making it a natural choice for senior dogs or breeds prone to cognitive decline. Its anti-allergic effects also help stabilize immune responses, making it useful for dogs with skin issues, seasonal allergies, or food sensitivities.

Because Luteolin offers both mental and physical support, it works well in daily supplements that target long-term wellness. Whether your dog is aging, allergy-prone, or just needs a cognitive edge, Luteolin delivers protective, plant-based support.

Vitexin is a calming flavonoid found in passionflower and hawthorn, known for its soothing effects on the nervous system and cardiovascular support. It helps reduce anxiety, improve circulation, and may protect the brain from oxidative stress. This makes it ideal for dogs who are anxious, easily overstimulated, or prone to nervous behaviors.

In addition to its calming properties, Vitexin has been studied for its potential neuroprotective and anti-inflammatory effects. It may help regulate stress-related responses and support emotional balance without sedation. For dogs who get anxious during travel, loud noises, or routine changes, Vitexin offers a natural, gentle way to stay calm and centered.

Its circulation-boosting effects may also support heart function and energy delivery to tissues, especially in aging dogs or those with cardiovascular concerns.

Wogonin is a flavonoid derived from the root of Baikal skullcap, a plant long used in traditional medicine for its calming and anti-inflammatory effects. In dogs, Wogonin offers natural support for anxiety, brain function, and immune balance. It works by influencing GABA receptors in the brain, helping promote calm behavior without sedation.

Wogonin also has neuroprotective properties that may help slow cognitive decline in aging dogs and support clear mental function in high-performing or overstimulated pups. Its anti-inflammatory benefits contribute to a healthy immune response and may help reduce long-term wear and tear on joints and organs.

This compound is ideal for dogs who are reactive, easily stressed, or showing early signs of confusion or cognitive dysfunction. It’s often combined with other flavonoids to support both emotional balance and long-term brain health.

Beta-Sitosterol is a plant-based compound known as a phytosterol, found naturally in seeds, nuts, and vegetable oils. It’s recognized for its cholesterol-balancing properties and its ability to support heart health and immune system function. In dogs, it can help regulate inflammation and maintain a healthy cardiovascular system, especially as they age.

This compound is also studied for its role in supporting prostate health and reducing symptoms related to benign prostatic hyperplasia (BPH) in male dogs. Additionally, Beta-Sitosterol may help modulate immune responses, offering support for dogs with seasonal sensitivities or chronic inflammation.

As a well-rounded wellness ingredient, Beta-Sitosterol works well in multi-functional formulas that target longevity, resilience, and full-body support.

Naringenin is a citrus-derived flavonoid found in grapefruits and oranges, known for its powerful antioxidant and anti-inflammatory effects. It helps protect cells from oxidative damage and supports key metabolic processes that influence energy levels, blood sugar balance, and fat metabolism in dogs.

This compound has been studied for its ability to improve insulin sensitivity and promote healthy lipid profiles, making it especially beneficial for overweight dogs or those prone to metabolic imbalances. Naringenin also supports cardiovascular function by helping maintain normal blood pressure and improving circulation.

Whether your dog is dealing with weight issues, low energy, or general inflammation, Naringenin offers clean, natural support for maintaining metabolic balance and overall wellness.

Catechins are a group of flavonoids found predominantly in green tea. Known for their powerful antioxidant activity, they help neutralize free radicals, reduce inflammation, and support heart, brain, and metabolic health in dogs. Their cellular protection benefits make them one of the most versatile flavonoids in natural wellness.

Catechins have been studied for their ability to improve cholesterol levels, enhance blood vessel function, and even assist in weight management by boosting fat oxidation and metabolism. For dogs with high energy needs, weight concerns, or aging-related health issues, Catechins offer broad-spectrum support.

Their neuroprotective potential may also play a role in maintaining mental clarity and cognitive resilience, especially in senior dogs. As part of a daily flavonoid blend, Catechins contribute to full-body wellness and long-term vitality.